What disease does digoxin tablets treat?
Digoxin tablets are a drug commonly used to treat heart disease, especially in the treatment of heart failure and certain arrhythmias. This article will introduce in detail the indications, mechanism of action, usage, dosage and precautions of digoxin tablets, and combine it with hot topics on the Internet in the past 10 days to help readers fully understand this drug.
1. Basic information about digoxin tablets
Digoxin tablets are cardiac glycosides that mainly improve cardiac function by enhancing myocardial contractility and regulating heart rate. The following are the main uses of digoxin tablets:
| Indications | illustrate |
|---|---|
| chronic heart failure | Used to improve heart function and relieve symptoms such as dyspnea, edema, etc. |
| atrial fibrillation | Used to control ventricular rate and reduce symptoms such as heart palpitations |
| atrial flutter | Assists in regulating heart rate and improves heart pumping function |
2. The mechanism of action of digoxin tablets
Digoxin tablets inhibit the sodium-potassium ATPase in myocardial cells and increase the intracellular calcium ion concentration, thereby enhancing myocardial contractility. At the same time, it can also slow down atrioventricular node conduction and lower heart rate by regulating the autonomic nervous system. Here is a detailed description of its mechanism of action:
| effect | mechanism |
|---|---|
| positive inotropic effect | Enhance myocardial contractility and improve heart pumping efficiency |
| negative frequency effect | Slow down the heart rate and reduce myocardial oxygen consumption |
| electrophysiological effects | Prolong the refractory period of the atrioventricular node and slow down the conduction velocity |
3. Usage and dosage of digoxin tablets
The usage and dosage of digoxin tablets must be determined by the doctor based on the patient's specific conditions. The following is a reference for common usage and dosage:
| crowd | initial dose | maintenance dose |
|---|---|---|
| aldult | 0.125-0.25 mg/day | 0.0625-0.125 mg/day |
| elderly | 0.0625 mg/day | 0.0625 mg/day |
| People with renal insufficiency | 0.0625 mg/day | 0.0625 mg/every other day |
4. Precautions for taking digoxin tablets
Although digoxin tablets are effective, improper use may lead to serious side effects. The following are precautions when using:
| Things to note | illustrate |
|---|---|
| Monitor blood drug levels | Avoid digoxin poisoning, narrow therapeutic window |
| Avoid hypokalemia | Low potassium increases risk of digoxin toxicity |
| drug interactions | Caution is required when combined with certain antibiotics, diuretics, etc. |
5. Popular topics related to Gaoxin in the past 10 days across the Internet
Combined with the hot topics on the Internet in the past 10 days, the following are the hot topics of discussion about digoxin tablets:
| topic | heat index |
|---|---|
| Application of digoxin tablets in elderly patients with heart failure | high |
| Early recognition and treatment of digoxin poisoning | Middle to high |
| Interactions between digoxin and other drugs | middle |
| Research progress on alternative medicines for digoxin tablets | low middle |
6. Summary
Digoxin tablets, as a classic drug for the treatment of heart disease, play an irreplaceable role in the treatment of heart failure and arrhythmia. However, due to its narrow therapeutic window, patients need to strictly follow the doctor's instructions and regularly monitor blood drug concentrations and electrolyte levels. Recent discussions about digoxin have focused on drug safety and drug interactions in elderly patients, reflecting public concerns about the safety of this drug.
Through the structured data in this article, we hope that readers can have a clearer understanding of the indications, mechanisms of action and precautions of digoxin tablets, and provide a reference for rational drug use.
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