What is cholangiocarcinoma
Cholangiocarcinoma is a malignant tumor originating from bile duct epithelial cells and is a type of biliary system tumor. In recent years, with the deepening of medical research and the improvement of public health awareness, cholangiocarcinoma has gradually become a hot topic. This article will give you a detailed introduction to the definition, classification, symptoms, diagnosis and treatment of cholangiocarcinoma based on hot content from the entire Internet in the past 10 days, and provide relevant structured data.
1. Definition and classification of cholangiocarcinoma
Cholangiocarcinoma can be divided into the following three categories based on where it occurs:
| Type | site of occurrence | Proportion |
|---|---|---|
| intrahepatic cholangiocarcinoma | bile ducts in the liver | About 10%-20% |
| hilar cholangiocarcinoma | Portal bile duct | About 50%-60% |
| distal cholangiocarcinoma | distal common bile duct | About 20%-30% |
2. Symptoms of cholangiocarcinoma
The early symptoms of cholangiocarcinoma are not obvious. As the disease progresses, the following symptoms may appear:
| Symptoms | Description |
|---|---|
| Jaundice | Yellowing of skin and sclera, darker urine |
| abdominal pain | Dull or distended pain in the right upper quadrant |
| weight loss | Weight loss without apparent cause |
| Itchy skin | caused by cholestasis |
3. Diagnostic Methods of Cholangiocarcinoma
Currently, the diagnosis of cholangiocarcinoma mainly relies on the following examination methods:
| Check method | function |
|---|---|
| blood test | Test liver function and tumor markers (such as CA19-9) |
| Imaging examination | B-ultrasound, CT, MRI, etc. to observe the location and size of the tumor |
| Endoscopic retrograde cholangiopancreatography (ERCP) | Direct visualization of bile ducts and biopsy |
4. Treatment methods for cholangiocarcinoma
Depending on the stage of the tumor and the patient’s physical condition, treatment options include:
| Treatment | Applicable situations |
|---|---|
| surgical resection | Early stage tumor, no distant metastasis |
| Chemotherapy | Late or postoperative adjuvant treatment |
| radiotherapy | Local control of tumor growth |
| targeted therapy | Target specific gene mutations (such as FGFR2 fusions) |
5. Hot topics on the Internet in the past 10 days and discussions related to cholangiocarcinoma
In the past 10 days, the discussion of cholangiocarcinoma has mainly focused on the following hot spots:
| topic | heat index |
|---|---|
| Early screening methods for cholangiocarcinoma | high |
| Progress of new targeted therapy drugs | Middle to high |
| Association between cholangiocarcinoma and cirrhosis | in |
6. Summary
Cholangiocarcinoma is a highly malignant tumor, and early diagnosis and treatment are crucial to prognosis. In recent years, with the advancement of targeted therapy and immunotherapy, patient survival rates have improved. The public should pay attention to their own health and have regular physical examinations, especially those with a history of chronic biliary disease. If you have suspected symptoms, please seek medical examination in time.
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